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Rat Anti-Mouse F4/80 mAb (AF488)

簡要描述:Rat Anti-Mouse F4/80 mAb (AF488)

  • 產品型號:781021
  • 廠商性質:生產廠家
  • 更新時間:2025-08-21
  • 訪  問  量:35
產品詳情
同源性比對:
Q61549
稀釋比
FC-5μL per test for million cells or whole blood in 100 μL volume.
SwissProt ID
Q61549
宿主
Rat
偶聯物
AF488. Ex:490nm.Em:525nm.
修飾
Unmodified
基因 ID
13733
基因名
Mouse F4/80
亞型
IgG2b
克隆性
Monoclonal Antibody
克隆號
CI:A3-1
免疫原
A synthesized peptide derived from Mouse F4/80
研究領域
Immunology
背景信息
F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.
純化方式
Affinity Purified
形式
Liquid
存儲緩沖液
Liquid in PBS with 0.05% Proclin300, 1% BSA
保存溫度
Store at 2-8°C..Avoid light.Avoid freeze/thaw cycles.

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